tDCS for Cognitive Issues in Breast Cancer Survivors
tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment
Recruiting
N/AInterventional Study
Breast Cancer SurvivorObesity, Overweight
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Female
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
University of Helsinki · Other
Who this trial is looking for
This trial is looking for women who have survived breast cancer and may be experiencing cognitive problems. Participants will receive a specific type of brain stimulation for six weeks and undergo various tests to see how it affects their thinking.
Are You a Good Fit for This Trial?
Rules you outDementiaAlzheimer's diseaseMultiple sclerosisParkinson's disease
You may be able to join if
I am female
I am over 18 years old
I was diagnosed with breast cancer in the last 5 years
I have completed all my cancer treatments at least 3 months ago
I can meet study requirements and have internet access
I speak either Finnish or English
I have normal or corrected vision and hearing
I am right-handed
You may not be able to join if
I have received cancer treatment in the last 3 months
I have a history of childhood-onset cancer
I have acute eczema on my scalp
I have been diagnosed with dementia or other serious brain conditions
I have lost consciousness for more than five minutes due to a brain injury in the last 10 years
I have a history of stroke
I suffer from claustrophobia
I am pregnant or breastfeeding
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving …
The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving sham stimulation (a placebo condition where participants believe they are receiving stimulation, but are not).
Participants will:
* Undergo a baseline MRI session
* Receive either active or sham tDCS for six weeks
* Undergo a follow-up MRI session
* Complete cognitive tests and respond to psychosocial questionnaires before, during, and after the tDCS intervention
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Female
* Over 18 years old
* Diagnosed with primary adult-onset breast cancer within the last 5 years
* Completed all active cancer treatments at least 3 months prior to study participation
* Capable of fulfilling study requirements, including having internet access.
* Fluent …
Inclusion Criteria:
* Female
* Over 18 years old
* Diagnosed with primary adult-onset breast cancer within the last 5 years
* Completed all active cancer treatments at least 3 months prior to study participation
* Capable of fulfilling study requirements, including having internet access.
* Fluent in either Finnish or English
* Have normal or corrected vision and hearing
* Right-handed (based on the Edinburgh Handedness Inventory score; Oldfield, 1971)
Exclusion Criteria:
* Have received primary cancer treatment (chemotherapy, radiotherapy, immunotherapy, or surgery) within the last 3 months
* Have a history of childhood-onset cancer
* Present with acute eczema on the scalp
* Diagnosed with dementia, Alzheimer's disease, multiple sclerosis, or - Parkinson's disease
* Have experienced unconsciousness for more than five minutes due to a head/brain injury within the last 10 years
* Have a history of stroke or transient ischemic attack
* Suffer from claustrophobia
* Are pregnant or breastfeeding
* Have any of the following medical implants or devices: cardiac implantable electronic devices, metallic intraocular foreign bodies, neurostimulation systems, cochlear/ear implants, drug infusion pumps, catheters with metal components, metallic fragments (e.g., bullets), cerebral aneurysm clips, magnetic dental implants, tissue expanders, artificial limbs, non-removable piercings, or face tattoos.
* Weight exceeding 250 kg (the MRI table weight limit) or they are unable to fit within the 70 cm diameter bore of the MRI machine
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