FTT PET/CT in Pancreatic Neuroendocrine Tumors

Recruiting Phase 1 Interventional Study
Neuroendocrine Carcinoma Metastatic Pancreatic Tumors
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Diagnostic
Participants needed
12 (estimated)
Sponsor
Abramson Cancer Center at Penn Medicine · Other
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About This Trial
A pilot study to evaluate the expression of PARP-1 in patients with pancreatic neuroendocrine tumors will be conducted. This will be done via the use of a novel PET imaging agent, \[18F\]FluorThanatrace (\[18F\]FTT). A total of 12 patients will be enrolled. Patients will undergo a study imaging assessment using a whole-body PET CT scanner. Dynamic images will be obtained beginning immediately prio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients must be ≥ 18 years of age. 2. Clinical diagnosis of a metastatic or unresectable grade 1, grade 2 or grade 3 (G1/G2/G3) pancreatic neuroendocrine tumor. 3. Have at least one lesion on clinical imaging (e.g. CT/MRI/PET/CT/ultrasound) that is ≥ 1.5 cm in size. 4. Patie…
Contacts

Erin K Schubert, MS

215-573-6569

erinschu@pennmedicine.upenn.edu

CONTACT