Review the details below, then apply to join this clinical trial.
At a Glance
Age
50 – 90
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
30 (estimated)
Sponsor
Cristina Colon-Semenza · Other
Who this trial is looking for
This trial is looking for adults aged 50 to 80 with Parkinson's disease. Participants will take either a special amino acid supplement or a placebo daily for 6 months and attend three lab visits for health assessments.
Are You a Good Fit for This Trial?
Must be takingDopamine replacement medication
You may be able to join if
I am between 50 and 80 years old.
I have been diagnosed with Parkinson's disease.
I have been using dopamine replacement medication for at least 2 years.
I have been on a stable dose of my medication for at least 3 months.
You may not be able to join if
I have cognitive impairment as determined by a phone screening.
I have been diagnosed with Parkinsonism or atypical Parkinson's disease.
I am taking a dopamine antagonist.
I have any unstable medical condition.
I have had deep brain stimulation surgery.
I have had gastric or bowel resection surgery.
I have contraindications to blood draws.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are:
Does the tailored amino acid supplement increase essential amino acids (nutritional status)?
Does the tailored amino acid supplem…
The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are:
Does the tailored amino acid supplement increase essential amino acids (nutritional status)?
Does the tailored amino acid supplement increase an antioxidant (complex amino acid) and decrease an amino acid associated with oxidative stress?
Does the tailored amino acid supplement improve physical and mental health compared to a placebo supplement?
Researchers will compare the tailored amino acid supplement to a placebo (a look-alike substance that contains no active ingredients) to see if the tailored amino acid supplements work to support health for people with Parkinson's disease.
Participants will:
Take the tailored amino acid supplement or a placebo every day for 6 months, visit the lab at baseline, after 3 months, and after 6 months for fasting blood draws, body composition assessment, and physical and mental health testing and keep a diary of their food intake and supplement intake.
Trial Locations
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Eligibility Criteria
Inclusionary Criteria:
* Male and Females.
* 50-80 Years.
* Previous diagnosis of idiopathic Parkinson's Disease by patient report.
* Use of dopamine replacement medication (e.g. levodopa) for at least 2 years.
* On a stable dose of dopamine replacement medication for at least 3 months with no plan…
Inclusionary Criteria:
* Male and Females.
* 50-80 Years.
* Previous diagnosis of idiopathic Parkinson's Disease by patient report.
* Use of dopamine replacement medication (e.g. levodopa) for at least 2 years.
* On a stable dose of dopamine replacement medication for at least 3 months with no plans for change in the next two months.
Exclusionary criteria
* Apparent cognitive impairment as determined by phone screening (Telephone Interview for Cognitive Status \<29).
* Diagnosis of Parkinsonism or atypical Parkinson's Disease.
* Prescription of Dopamine antagonist.
* Any unstable medical condition.
* Use of Deep Brain Stimulation.
* Gastric or Bowel resection surgery.
* Contraindications to blood draw.
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