Efficacy and Safety of Radical Prostatectomy (RP) With or Without Salvage Radiotherapy Versus RP With Extended Pelvic Lymph Node Dissection for Localized Intermediate- and High-risk Prostate Cancer With a Briganti Nomogram≥7%

Recruiting N/A Interventional Study
Prostate Cancer Prostate Adenoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Male
Study type
Interventional
Purpose
Treatment
Participants needed
270 (estimated)
Sponsor
Ruijin Hospital · Other
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About This Trial
The goal of this clinical trial is to evaluate efficacy and safety of radical prostatectomy (RP) with or without salvage radiotherapy versus RP with extended pelvic lymph node dissection (ePLND) in males who have localized intermediate/high-risk prostate cancer with a Briganti nomogram no less than 7%. The main questions this study aim to answer are: 1. Is RP with or without salvage radiotherapy …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Provided signed and dated informed consent form. * Be male aged 18-80 years at consent. * Commit to protocol compliance and complete all study procedures. * Medically fit to tolerate interventions, including PSMA PET imaging, RARP, pelvic radiotherapy. * Diagnosis of localized…
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