Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM

Recruiting Phase 4 Interventional Study
Preterm PROM (Pregnancy)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 50
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
Eastern Virginia Medical School · Other
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About This Trial
Data on the optimal mode of labor induction after preterm prelabor rupture of membranes (PPROM) is lacking. Studies have shown no difference between oxytocin and misoprostol use for labor induction in this cohort (1). The preponderance of evidence from term pregnancies suggests that Foley catheter coupled with oxytocin is better than oxytocin alone, with a higher rate of delivery within 24 hours w…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients 18-50 years of age; * The patient is fluent in English, physically and mentally able to understand the informed consent, and is willing to participate in this study; * PPROM; * Cervical dilation \</= 2cm * Fetal cephalic presentation; * The patient is between 34 weeks…
Contacts

Kristin Ayers, MPH

7574460529

ayerskl@evms.edu

CONTACT