Metformin for Premature Infants With Bronchopulmonary Dysplasia
Recruiting
Early Phase 1
Interventional Study
Bronchopulmonary Dysplasia (BPD)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 7 Days – 6 Months
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- Medical College of Wisconsin · Other
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About This Trial
The overall objective of this study is to investigate the role of metformin in decreasing lung injury and promoting lung growth in premature infants. There are two phases to this pilot study. For Phase 0, the goal is to investigate the safety and tolerance of oral metformin in premature who have been diagnosed with bronchopulmonary dysplasia (BPD) at 36-44 weeks gestation. For Phase 1, the goal is…
Trial Locations
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Eligibility Criteria
Inclusion Criteria Phase 0:
* Birth gestational age of \< 29 weeks AND
* Postnatal age between 8 and 22 weeks AND
* Diagnosed with BPD at 36 weeks postnatal age
Inclusion Criteria Phase 1:
* Birth gestational age of \< 29 weeks, AND
* Requiring mechanical ventilation or positive pressure support …
Contacts