Facial Training Tool for Cognitive Impairment
FACE Phase II (a Stage II Trial)
Recruiting
Phase 1
Phase 2
Interventional Study
MCI
Subjective Cognitive Decline (SCD)
Mild Behavioral Impairment
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 60 – 89
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 80 (estimated)
- Sponsor
- Stanford University · Other
Who this trial is looking for
This trial is looking for older adults who are at risk for Alzheimer's disease and want to improve their cognitive skills. Participants will use a new tool that monitors their facial expressions to help keep them engaged in at-home cognitive training.
Are You a Good Fit for This Trial?
You may be able to join if
- I am aged 60-89
- I can speak English
- I live independently or in assisted living
- I have normal vision and hearing
- I have been stable on my anti-depressants or anxiety medications for at least 7 days
- I have been stable on memory medications for at least 3 months
- I do not have any serious neurological disorders
You may not be able to join if
- I am enrolled in another cognitive improvement study
- I live in a nursing home
- I have been diagnosed with Multiple Sclerosis
- I have had a traumatic brain injury (TBI)
- I have chronic heart failure
- I have Parkinson's disease
- I have dementia
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
How to ensure adherence to computerized cognitive training in unsupervised circumstances (e.g., at-home, self-administered) in older adults at risk for Alzheimer's disease (AD) or AD related dementia (AD/ADRD) is understudied. The objective of the R33 study is to test a novel facial expression-based personalization engine (FPE) for monitoring and modulating real-time effective engagement, with an …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. English speaking
2. Aged 60-89
3. Living in a home, or independent- or assisted-living facility
4. Adequate visual and hearing acuity
5. Anti-depressants, antipsychotics, and/or anxiolytics have been stable for at least 7 days
6. Memory medications have been stable for at lea…
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