Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

Recruiting Phase 4 Interventional Study
Drain Output After Breast Reduction Surgery Breast Reductions
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Female
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
160 (estimated)
Sponsor
Massachusetts General Hospital · Other
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About This Trial
This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned to receive either intravenous TXA or no TXA during surgery. Additionally, one breast will receive TXA through the surgical drain, while the other will receive saline. This approach allows to compare th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older * Elective bilateral breast reduction * Patient understands and is willing to participate in the study * Patient willing to and capable of providing informed consent Exclusion Criteria: * Age less than 18 years old * Prior radiation to the breas…
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