Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Recruiting Phase 2 Interventional Study
Brain Metastases, Adult Brain Tumor - Metastatic Brain Metastases From Non-small Cell Lung Cancer (NSCLC) Brain Metastases From Extra-cranial Solid Tumors
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Ayal A. Aizer, MD · Other
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About This Trial
The goal of this study is to evaluate the feasibility and effectiveness of same-day radiation planning and treatment. The study will shorten the time interval between radiation planning (radiation mapping) and radiation treatment. The intent of this shorter time interval is to increase the likelihood that the brain metastases being treated remain fully within the high-dose radiation fields. Parti…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Participants must have a biopsy proven solid malignancy with at least one intact, residual or recurrent, intracranial lesion radiographically consistent with or pathologically proven to be a brain metastasis meeting one of the following criteria: 1. Growth of 1.0mm per we…
Contacts

Ayal A Aizer, MD, MHS

(617) 732-7560

aaaizer@partners.org

CONTACT

Ivy B Ricca, BA

(617) 582-8927

iricca@mgb.org

CONTACT