HEARTS Trial for Thoracic Cancers
Recruiting
Phase 2
Interventional Study
Non-Small Cell Lung Cancer (Stage III)
Esophageal Cancer Stage I-III
Esophagogastric Cancer Stage I-III
Thymoma and Thymic Carcinoma Stage II-III
Other Cancers in the Thoracic Region
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- University of Wisconsin, Madison · Other
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About This Trial
The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart.
The main question it aims to answer is whether MRgART affects the heart differently than LINAC.
Participants will:
* Receive radiation the…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years at the time of consent.
* Dosimetric eligibility criteria met using endpoints from QUANTEC (\>10% of heart receives \> 25 Gy) as determined through rapid auto-planning
* Participants with histologically or cytologically proven AJCC, 8th edition including:
* …
Contacts