IPX-203 for Parkinson's Disease Management

BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

Recruiting Phase 4 Interventional Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
40 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
22 (estimated)
Sponsor
The Cleveland Clinic · Other
Who this trial is looking for

This trial is looking for people aged 40 and older with Parkinson's disease who are currently treated with a stable medication regimen. Participants will use a wearable device to help measure their symptoms while taking IPX-203.

Are You a Good Fit for This Trial?
Must be taking CD-LD

You may be able to join if

  • I am 40 years or older.
  • I have been diagnosed with Parkinson's disease.
  • I respond to levodopa treatment.
  • I have a baseline MDS-UPDRS score greater than 20.
  • I have been on a stable medication regimen for at least four weeks.
  • I experience at least 2 hours of off time each day.
  • I can use a wearable device.

You may not be able to join if

  • I have severe dyskinesia.
  • I am currently using device-aided therapies for advanced Parkinson's disease.
  • I use controlled-release levodopa except for a single bedtime dose.
  • I use on-demand therapy unless I can stop it during the trial.
  • I have a diagnosis of dopamine dysregulation syndrome.
  • I have a history of dementia or a MOCA score below 23.
  • I have significant medical issues that could interfere with the trial.
  • I am enrolled in other clinical trials with active medications.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial
The purpose of this study is to evaluate the effect of IPX203 (Crexont®) - the newest extended-release levodopa formulation - on the duration and quality of good on time, using a wearable device to monitor symptoms. 'Good on time' refers to a period (minutes to hours) when a patient experiences optimal symptom control due to effective medication and has better overall functioning without troubleso…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * \- Participant is 40 years or older * Diagnosed with idiopathic Parkinson's disease and is deemed to be levodopa responsive * Baseline MDS-UPDRS score in OFF-state is \> 20 * Patient is being treated with a stable regimen of CD-LD for at least four weeks * The minimum most fre…
Contacts

Saar Anis, MD

216 678-8896

ANISS2@ccf.org

CONTACT

Mary Carmell Beukemann

216-372-2867

beukemm@ccf.org

CONTACT