Family Communication After Genetic Testing for Colorectal Cancer

Family Communications After Genetic Testing

Recruiting N/A Interventional Study
Colon Adenocarcinoma Colorectal Adenocarcinoma Rectal Adenocarcinoma Stage I Colon Cancer AJCC v8 Stage I Colorectal Cancer AJCC v8 Stage I Rectal Cancer AJCC v8 Stage II Colon Cancer AJCC v8 Stage II Colorectal Cancer AJCC v8 Stage II Rectal Cancer AJCC v8 Stage III Colon Cancer AJCC v8 Stage III Colorectal Cancer AJCC v8 Stage III Rectal Cancer AJCC v8 Stage IV Colon Cancer AJCC v8 Stage IV Colorectal Cancer AJCC v8 Stage IV Rectal Cancer AJCC v8
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Screening
Participants needed
4,186 (estimated)
Sponsor
Alliance for Clinical Trials in Oncology · Other
Who this trial is looking for

This trial is looking for patients with newly diagnosed colorectal cancer and their family members. Participants will help improve how genetic testing information is shared with relatives.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old.
  • I have been diagnosed with colorectal adenocarcinoma stage I to IV.
  • I have at least two living first-degree relatives I can share my diagnosis with.
  • I have not received germline genetic testing in the last two years.
  • I can speak and read English or Spanish.
  • I have not been diagnosed with dementia or cognitive impairment.

You may not be able to join if

  • I have stage 0 or in-situ colorectal cancer.
  • I have a known psychiatric disorder affecting my judgment.
  • I cannot explain genetic test results to my family.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
This clinical trial compares patient (proband)-mediated communication to provider-mediated communication for improving genetic testing in first-degree relatives of patients with newly diagnosed colorectal cancer. It is estimated that 30% of cases of colorectal cancer have a genetic basis and about 15% of these patients have a disease-causing (pathogenic) inherited (germline) variant in a cancer su…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * STEP 1 PROBANDS: Age \>= 18 years * STEP 1 PROBANDS: Patients with a newly diagnosed (within 3 months of registration), primary colorectal adenocarcinoma, stage I to IV * Histologically proven stage I to IV colon or rectal adenocarcinoma (any T or N, M+). Tumors deemed to o…
Contacts

Rachel Wills

773-702-9814

rwills@bsd.uchicago.edu

CONTACT