SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients

Recruiting Phase 4 Interventional Study
Kidney Transplantation Recipients Sodium-Glucose Transporter 2 Inhibitors Non-Diabetic Patients Randomized Controlled Trial Placebo Control Design
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
88 (estimated)
Sponsor
Odense University Hospital · Other
Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
This clinical trial investigates whether 18 months of daily SGLT2i (10 mg Forxiga) preserves kidney function and evaluates safety, based on eGFR changes and adverse event occurrence in non-diabetic kidney transplant recipients. The main questions it aims to answer are: * Does SGLT2i versus placebo, as an add-on to standard care, preserve kidney transplant function in non-diabetic recipients? * I…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Obtained written informed consent * Male or female patients, age ≥ 18 years. * Non-diabetic KTR * \> 6 months post-transplant * eGFR\> 25 ml/min/1.73m2 within the last 3 months pre randomization * Immunosuppressive must include Tacrolimus * Negative plasma hCG in fertile women…
Contacts

Lotte B Lange, MD

+45 40863392

lotte.borg.lange@rsyd.dk

CONTACT

Lotte B Lange, MD

+4540863392

lotte.borg.lange@rsyd.dk

CONTACT