DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI

Recruiting Phase 2 Interventional Study
Esophageal Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
Tianjin Medical University Cancer Institute and Hospital · Other
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About This Trial
This is a multi-center, Phase II clinical study aiming to evaluate the efficacy, safety, and organ preservation feasibility of definitive concurrent chemoradiotherapy versus surgery in patients with locally advanced resectable esophageal squamous cell carcinoma (ESCC) who achieve clinical complete response/partial response (cCR/PR) after neoadjuvant chemo-immunotherapy. A total of 120 eligible su…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Volunteered to participate, cooperated with follow-up visits. 2. Aged 18 - 75 years (inclusive), male or female. 3. Histologically confirmed locally advanced resectable ESCC, clinically staged as Stage II - IVa (cT1N1-3M0, cT2-4aN0-3M0 before treatment; 8th AJCC), and achieve…
Contacts

Wencheng Zhang, M.D.

02223340123

zhangwencheng@tjmuch.com

CONTACT