Protease Regulation and Impact of Sodium as Mechanisms of Inflammation in IBD
Recruiting
Observational Study
Crohns Disease
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 70
Sex
Any
Study type
Observational
Participants needed
300 (estimated)
Sponsor
McMaster University · Other
Who this trial is looking for
This trial is looking for adults aged 18 to 70 with Crohn's disease to study how salt affects gut health. Participants will explore how salt intake might relate to inflammation and symptoms of their condition.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 70 years old
I have been diagnosed with Crohn's disease
I am willing to sign consent to join the study
I can follow the study procedures
You may not be able to join if
I have taken antibiotics, antibacterial agents, or probiotics in the last 8 weeks
I have a history of alcohol or drug abuse
I am pregnant
I have a serious concurrent illness that could affect the study
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may…
The study looks at how eating salt affects gut health in people with Crohn's disease. The aim of the study is to find out whether eating more salt increases the breakdown of proteins in the gut and if this makes inflammation and symptoms worse. By studying the link between salt, gut bacteria and inflammation, the study hopes to improve diet advice for people with Crohn's disease. This research may help find specific foods that affect the disease and lead to better, more personalized nutrition plans.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18 and 70 years of age
* Crohn's disease diagnosis
* Willing and able to sign written informed consent prior to study entry
* Able to comply with the study procedures, in the opinion of the investigator
Exclusion Criteria:
* Antibiotics, antibacterial agents, or probiotics, …
Inclusion Criteria:
* 18 and 70 years of age
* Crohn's disease diagnosis
* Willing and able to sign written informed consent prior to study entry
* Able to comply with the study procedures, in the opinion of the investigator
Exclusion Criteria:
* Antibiotics, antibacterial agents, or probiotics, currently, or within the last 8 weeks
* Alcohol or drug abuse
* Pregnancy
* Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be a risk or that could interfere with data collection
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