A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease

Recruiting Phase 1 Interventional Study
Parkinson's Disease (PD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
24 (estimated)
Sponsor
Fujita Health University · Other
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About This Trial
This study will test the safety of twice-daily oral dosing of combined febuxostat and inosine in 24 patients with Parkinson's disease. Participants will receive one of the four regimens, taken twice daily for 12 weeks: Who can join: Adults with early-stage Parkinson's disease on stable medication regimens. What participants do: * Take their assigned dose twice daily (morning and evening) for 12…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Able to provide voluntary written informed consent. 2. Receiving stable Parkinson's disease medication (no changes in type or dose) for at least 3 months before enrollment. 3. Age 18 to 80 years at the time of consent. 4. Diagnosed with Parkinson's disease by a specialist acc…
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