Targeted Abdominal CT in Conjunction With Lung Cancer Screening

1. For the individual level randomisation to invitation control or invitation intervention Inclusion criteria: To be randomised at the individual level to receive an invitation letter for LCS (standard of care; invitation control) versus invitation letter for LCS with potential for an additional abdominal scan (invitation intervention): * Be eligible to be invited to the first round of a West Yorkshire and Harrogate LCS or a Humber and North Yorkshire Cancer Alliance LCS (i.e. have been identified as a smoker or ex-smoker and registered as living within the relevant LCS catchment area). * Be registered with a GP in England. * Be aged 55-70 years 364 days old at the date of invitation. Exclusion criteria • None 2. Eligibility criteria for the cluster level randomisation to scan intervention or scan control Inclusion criteria a): To be eligible for the cluster level randomisation the participant must: * Have been individually randomised to the invitation intervention arm * Have booked in for a LCS assessment Inclusion criteria b): To receive the CT Thorax plus ANCCT, the participant must: * Have been randomised to the scan intervention cluster * Be invited to attend for a LDCT Thorax based upon scores on either PLCOM2012 or Liverpool Lung Project (LLP) risk prediction models (PLCOM2012 risk of ≥1.51% over six years or LLPver2 five-year risk of ≥2.5%)14 during the LCS assessment. * Have attended the lung scan appointment * Have given electronic or written informed consent to participate Exclusion criteria Existing LCS exclusion criteria: * Participant does not have capacity to give consent (standard criteria for assessing capacity apply). * Weight or physical size exceeds restrictions for scanner (\>200kg). * Participant unable to lie flat. * Poor physical fitness such that treatment with curative intent would be contra-indicated. * Participants who have had a full CT Thorax that meets the image reconstruction parameters of the programme in the last 12 months are not excluded from the lung screening programme, but would have their CT Thorax appointment deferred until 12 months have elapsed since that last scan, provided they still meet all inclusion criteria and have no exclusion criteria - if the deferred appointment is within the timeframe for TACTICAL1, they remain eligible but if deferred appointment is outside the timeframe for TACTICAL1 they would not be eligible. Additional TACTICAL1 exclusion criteria: • Had an abdominal CT in the previous 12 months or has one booked within the next 3 months. * For HNY, this is checked before the LCS assessment. Therefore, participants will be excluded before the LCS assessment. * For WYH, this is only checked after the LCS assessment. Therefore, anyone having had an abdominal CT in the previous 12 months or with one booked within the next 3 months will be excluded at this point (see 8.6). 3. Eligibility criteria for the process evaluation Health care professionals: Healthcare professionals involved in the delivery of LCS in any of the study areas who agree to take part. Participants: People individually randomised to the invitation intervention arm who attend the LCS assessment or the scanning unit within the study period and who agree to be interviewed.