Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients
Recruiting
Phase 4
Interventional Study
Critical Illness
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 16 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 3,253 (estimated)
- Sponsor
- Scarborough General Hospital · Other
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About This Trial
In patients with critical illness, such as severe infections, heart attacks, or respiratory failure, most intensive care units (ICUs) measure magnesium levels and give supplemental doses of magnesium when levels are below certain targets. However, the best targets are unknown. The goal of this clinical trial is to study protocols for magnesium supplementation in people with critical illness, compa…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 16 years or older
* Admission orders written to a medical-surgical intensive care unit at a participating site
* Magnesium replacement protocol ordered
Exclusion Criteria:
* Prior enrollment in or withdrawal from MAGNOLIA trial
* Sustained ventricular tachycardia
* Pre-e…
Contacts