Remote Ischaemic Conditioning for Vascular Health
Remote Ischaemic Conditioning in the Older Person and Effects on Dynamic Cerebral Autoregulation
Recruiting
N/A
Interventional Study
Cerebral Autoregulation
Blood Pressure
Dynamic Cerebral Autoregulation
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 65 – 85
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 45 (estimated)
- Sponsor
- University of Nottingham · Other
Who this trial is looking for
This trial is looking for older adults aged 65 to 85 who can perform a treatment called Remote Ischaemic Conditioning (RIC) at home. Participants will receive RIC or a placebo for 6 weeks and attend two visits to measure their vascular health.
Are You a Good Fit for This Trial?
You may be able to join if
- I am aged 65 to 85.
- I can perform RIC independently at home.
- I am willing to give consent to join the study.
You may not be able to join if
- I have had active heart or brain problems in the last year.
- I have irregular heartbeats like atrial fibrillation.
- I have a condition affecting my blood vessels.
- I have a bleeding disorder.
- I have an injury or fracture to my upper limb.
- I am pregnant or breastfeeding.
- I have a history of mental illness.
- I have a history of neurological conditions like epilepsy.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
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Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Remote Ischaemic Conditioning (RIC) is the process of inducing short periods of ischaemia in a limb with the aim of improving vascular health systemically. Recent findings have demonsatrated efficacy in a variety of clinical settings. However, the ideal protocol of RIC \[dose\] is unknown. Dynamic Cerebral Autoregulation (dCA) has been shown to increase in response to RIC.
The goal of this trial …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Participant is willing and able to give informed consent for participation in the study
* Participant aged 65 - 85
* Participant is able to perform RIC independently at home
Exclusion Criteria:
* Active cardiovascular or cerebrovascular disease (acute event within the last 1…
Contacts