Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
Recruiting
N/A
Interventional Study
Magnesium Sulfate
Remifentanil
S 100beta
S100 Beta Protein, Human
Neuron-Specific Enolase
Brain Ischemia
Sevoflurane Anaesthesia
Propofol/Remifentanil
Ketamine
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 90
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 150 (estimated)
- Sponsor
- University General Hospital of Patras · Other
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About This Trial
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus surgery (FESS) performed under controlled hypotension. Patients are randomly assigned to receive either total intravenous anesthesia with propofol-remifentanil, propofol-…
Trial Locations
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Eligibility Criteria
Inclusion Criteria :
Adult patients (≥18 years old). Scheduled for F.E.S.S (Functional endoscopic sinus surgery ) under general anesthesia.
Able to provide informed consent
Exclusion Criteria:
Emergency surgery. ASA physical status IV-V. Severe hepatic or renal dysfunction. Known allergy or cont…
Contacts