No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
26 (estimated)
Sponsor
Makati Medical Center · Other
Who this trial is looking for
This trial is looking for adults who have mild skin issues like dryness or dermatitis. Participants will apply either a new product or petrolatum twice daily for 28 days and visit the clinic weekly for checkups.
Are You a Good Fit for This Trial?
Must not be takingCorticosteroidsCalcineurin inhibitorsBiologicsPhototherapy
You may be able to join if
I have been diagnosed with mild skin barrier dysfunction.
I have mild to moderate atopic dermatitis.
I have mild to moderate chronic plaque psoriasis.
I have contact dermatitis.
I have seasonal skin dryness.
I can apply the product as instructed.
I can provide informed consent.
I have matching test areas on my skin.
You may not be able to join if
I have severe atopic dermatitis or psoriasis.
I used corticosteroids or similar treatments in the last 2 weeks.
I have open wounds or infections on my skin.
I am pregnant or breastfeeding.
I have multiple nevi, tattoos, or dense body hair in the test areas.
I am immunocompromised.
I am allergic to the study product or petrolatum.
I cannot follow the visit schedule.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are:
Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers…
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are:
Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers will compare the novel barrier topical product to petrolatum (a gold standard occlusive barrier repair agent) to see how they are comparable in treating skin barrier dysfunction.
Participants will:
Apply the novel barrier topical product or petrolatum twice a day for 28 days Visit the clinic once a week for checkups and tests Keep a diary of their application of the assigned product
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Clinical diagnosis of mild skin barrier dysfunction, including:
* Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators.
* Mild to moderate chronic plaque psoriasis, defined as total body surface …
Inclusion Criteria:
* Clinical diagnosis of mild skin barrier dysfunction, including:
* Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators.
* Mild to moderate chronic plaque psoriasis, defined as total body surface area (BSA) involved: ≤3% to 10%.
* Contact dermatitis
* Seasonal xerosis or clinically evident skin dryness
* Symmetrical or bilateral test areas available (volar forearm)
* Willing and able to provide informed consent and adhere to study procedures
Exclusion Criteria:
* Failure to meet any of the above inclusion criteria
* Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatment
* Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within 2 weeks
* Open wounds or evidence of secondary infection at test sites
* Pregnant or breastfeeding women
* Multiple nevi, tattoos, dense body hair in the test areas
* Debilitated or immunocompromised subjects
* Known or suspected hypersensitivity to the interventional product (or its ingredients) or petrolatum
* Refusal or failure to comply with the schedule of visits at the test site.
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