Effects of Short-Chain Fatty Acids in Healthy Individuals
Metabolic Effects of Short-Chain Fatty Acids in Healthy Individuals
Recruiting
N/A
Interventional Study
Healhty
Other: Short-Chain Fatty Acid (SCFA)
Other: Butyrate (C4)
Other: Propionate (C3)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 40
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 10 (estimated)
- Sponsor
- University of Copenhagen · Other
Who this trial is looking for
This trial is looking for healthy men and women aged 18-40 to study how short-chain fatty acids, specifically propionate and butyrate, affect the body. Participants will take these acids during two visits and have their health monitored afterward.
Are You a Good Fit for This Trial?
You may be able to join if
- I am male or female.
- I am between 18-40 years old.
- My BMI is between 18.5 and 29.
You may not be able to join if
- I have diabetes.
- I have kidney or liver disease.
- I am pregnant, breastfeeding, or planning to become pregnant during the study.
- I am taking short-chain fatty acid supplements.
- I am taking vitamin B12 supplements.
- I have special dietary habits, like being vegan or on a ketogenic diet.
- I am receiving ongoing cancer treatment.
- I have a metabolic or absorption disorder.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The primary objective of this study is to investigate the acute physiological and metabolic effects of ingesting the short-chain fatty acids (SCFA)s propionate (three carbon atoms long; C3:0) and butyrate (C4:0) in healthy men and women. This aim will be addressed through a block-randomized cross-over study including two visits with acute intake of propionate and butyrate, respectively.
The hypot…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female.
* Age between 18-40 years old
* BMI between 18.5-29
Exclusion Criteria:
* Diabetes
* Kidney- or liver disease
* Pregnant, lactating or planning to become pregnant within the study period
* Supplementation with SCFAs
* Supplementation with B12 vitamin
* Specia…
Contacts