Urine Tumor DNA for Bladder Cancer Monitoring

Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer

Recruiting N/A Interventional Study
Non-muscle Invasive Bladder Cancer (NMIBC)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
56 (estimated)
Sponsor
Lahey Clinic · Other
Who this trial is looking for

This trial is looking for patients with non-muscle invasive bladder cancer. Participants will help determine if testing urine for tumor DNA can allow for less frequent check-ups with cystoscopy.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have high-risk bladder cancer
  • I have received BCG or gemcitabine/docetaxel treatment
  • I had a negative result after my initial therapy assessment

You may not be able to join if

  • I have high-risk NMIBC within the last 3 years
  • I have had prior induction intravesical therapy
  • I have variant histology
  • I have concurrent upper tract disease

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The goal of this clinical trial is to use urine tumor DNA (utDNA) as an indicator for non-muscle invasive bladder cancer to identify patients suitable for less frequent cystoscopy surveillance.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * AUA high-risk bladder cancer1 * Received induction BCG or gemcitabine/docetaxel * Negative initial post-induction therapy assessment (negative cytology and cystoscopy +/- biopsy) Exclusion Criteria: * High-risk NMIBC within 3 years * Prior induction intravesical therapy * Va…
Contacts

Linda Topjian

7817448420

Linda.M.Topjian@lahey.org

CONTACT

Colette Osborne

Colette.A.Osborne@lahey.org

CONTACT