Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean Delivery

Recruiting N/A Interventional Study
Postpartum Hemorrhage (Primary)
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 45
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Other
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About This Trial
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality, and its severity has been increasing globally, including in high-income countries. The most common cause of PPH is uterine atony occurring in about 70% of cases. Uterotonic agents, like oxytocin, are key in managing the third stage of labour to prevent PPH. Oxytocin is a short-acting medication and requires frequent dosing, howe…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Scheduled CD for patients ≥ 37 weeks excluding high risk factors for uterine atony 2. Neuraxial anesthesia as the primary anesthetic where intrathecal medications are the primary anesthetic Exclusion Criteria: 1. Risk factors for uterine atony including: 1. Overdistende…
Contacts

Mrinalini Balki, MD

416-586-4800

mrinalini.balki@uhn.ca

CONTACT

Kristi Downey, MSc

416-586-4800

kristi.downey@uhn.ca

CONTACT