Study of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Brain-first and Body-first PD

Recruiting Observational Study
Parkinson Disease Parkinsonian Disorders Brain Disease Basal Ganglia Diseases Synucleinopathies
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
150 (estimated)
Sponsor
Azienda USL Reggio Emilia - IRCCS · Government
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About This Trial
This observational study aims to systematically characterize a cohort of patients with early-stage Parkinson's disease (PD) attending the Movement Disorders Center of AUSL-IRCCS Reggio Emilia, Italy. PD is the second most common neurodegenerative disorder, affecting about 1% of individuals over 60 years of age. The project will explore clinical and biological differences between the recently propo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients diagnosed with PD according to the MDS Clinical Diagnostic Criteria for Parkinson's Disease divided into brain-first and body-first phenotypes, based on the presence or absence of a REM sleep behavior disorder diagnosed using ambulatory polysomnography methods accordi…
Contacts

Francesco Cavallieri, MD

francesco.cavallieri@ausl.re.it

CONTACT

Stefania Croci, BSc

stefania.Croci@ausl.re.it

CONTACT