To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
Recruiting
N/AInterventional Study
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
University of Alabama at Birmingham · Other
Who this trial is looking for
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This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and ridge preservation grafting followed by daily use of commercially available an essential oil (EO) mouthrinse and EDTA mouthrinse.
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Eligibility Criteria
Inclusion Criteria:
* Able to read and provide informed consent in English
* At least 18 years old
* Established and registered patient of the UAB School of Dentistry
* Patients presenting with one single rooted tooth determined to need extraction and simultaneous ridge preservation bone grafting f…
Inclusion Criteria:
* Able to read and provide informed consent in English
* At least 18 years old
* Established and registered patient of the UAB School of Dentistry
* Patients presenting with one single rooted tooth determined to need extraction and simultaneous ridge preservation bone grafting for future dental implant placement.
* Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the tooth planned for extraction.
* No anticipated need for surgical and/or endodontic care at teeth adjacent to the proposed surgical site during the study period.
Exclusion Criteria:
* Non-English speaking
* Age less than 18 years old or older than 85 years old
* Smokers/nicotine users (\>10 cigarettes or equivalent/day)
* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
* Multiple adjacent teeth require extraction and grafting
* Absence of adjacent teeth/implants on either side of the tooth to be extracted.
* Documented or suspected allergy or sensitivity to any study product
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