This study tests the hypothesis that, in women with preeclampsia without severe features, delivery management based on sFlt-1/PlGF would reduce the rate of induction of labor without worsening the rate of progression to preeclampsia with severe features and other maternal complications.
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Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years
* Singleton pregnancy
* Preeclampsia without severe features according to the ACOG definition
* Antegrade diastolic flow in the umbilical artery Doppler
* Gestational age between 36+0 and 38+6 weeks of gestation
* Gestational age confirmed by fetal crown-rump len…
Inclusion Criteria:
* Age ≥18 years
* Singleton pregnancy
* Preeclampsia without severe features according to the ACOG definition
* Antegrade diastolic flow in the umbilical artery Doppler
* Gestational age between 36+0 and 38+6 weeks of gestation
* Gestational age confirmed by fetal crown-rump length measurement in the first-trimester scan (from 11+0 to 13+6 weeks of gestation) or by in vitro fertilization dates
Exclusion Criteria:
* Fetal death
* Preeclampsia with severe features according to the ACOG definition, eclampsia, or any condition that requires immediate delivery
* Absent or reversed end-diastolic flow in the umbilical artery Doppler
* Non-reassuring CTG
* Decreased fetal movements
* Biophysical profile score ≤6
* Oligohydramnios
* Refusal to provide informed consent
* Fetal malformation
* Placental abruption
* Antiphospholipid antibody syndrome
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