Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening
Recruiting
N/AInterventional Study
Hereditary Cancer Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Female
Study type
Interventional
Purpose
Screening
Participants needed
1,000 (estimated)
Sponsor
Columbia University · Other
Who this trial is looking for
This trial is looking for women aged 18 to 55 who are receiving care during pregnancy or planning for pregnancy. Participants will consider whether they want genetic testing for hereditary cancer risks while getting standard prenatal care.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 55 years old.
I am receiving obstetrical-related care at a CUMC-affiliated site.
I have chosen to undergo obstetrical carrier screening.
I can speak and read in English or Spanish.
You may not be able to join if
I have completed a multigene hereditary cancer syndrome panel before.
I have a hematologic cancer or hematologic pre-cancer.
I have a history of an autologous bone marrow transplant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
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The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening.…
The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing among patients receiving routine prenatal care or preconception care. The goal is to evaluate the acceptability of hereditary cancer testing when offered alongside standard prenatal genetic screening. The study will also explore whether universal screening in this population could support early cancer prevention
Trial Locations
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Eligibility Criteria
Inclusion criteria:
* Age: 18 years - 55 years
* Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site
* Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider
* Patients with prior OCS but planned to repeat OCS are eligible
* Patients can s…
Inclusion criteria:
* Age: 18 years - 55 years
* Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site
* Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider
* Patients with prior OCS but planned to repeat OCS are eligible
* Patients can speak and read in English or Spanish
Exclusion criteria:
* Patients who have previously completed a multigene hereditary cancer syndrome panel
* Patients that have a hematologic cancer or hematologic pre-cancer
* Patients who have a history of an autologous bone marrow transplant
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