Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
Recruiting
N/A
Interventional Study
Cannabis Use
SCHIZOPHRENIA
Psychosis
rTMS
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 100 (estimated)
- Sponsor
- Vanderbilt University Medical Center · Other
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About This Trial
The central hypothesis is this: Brain circuits most relevant to cannabis use in schizophrenia are distinct from pathways identified in healthy controls who use cannabis. This study seeks to provide evidence that targeted stimulation of the DMN leads to both altered network activity and a concomitant behavioral change in cue-induced craving and cognitive performance in individuals with schizophreni…
Trial Locations
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Eligibility Criteria
Inclusion Criteria for Psychosis Participants:
* Age between 18-65 years
* Diagnosis of a psychotic disorder according to DSM-5 criteria and confirmed by SCID
* Current cannabis use of at least 2/10 on a Visual Analog Scale
* Current cannabis use (confirmed by urine cannabis testing)
* Must be able…
Contacts