Cisatracurium vs Rocuronium for Chronic Kidney Disease

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

Recruiting Phase 4 Interventional Study
Post Operative Pulmonary Complications Neuromuscular Blockade General Anesthesia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 80
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
490 (estimated)
Sponsor
The University of Texas Medical Branch, Galveston · Other
Who this trial is looking for

This trial is looking for patients with chronic kidney disease who need surgery with general anesthesia. Participants will help researchers find out which medication combination is safer during and after surgery.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 80 years old.
  • I have chronic kidney disease as defined by my doctor.
  • I am able and willing to provide signed consent.
  • I need surgery that requires general anesthesia and neuromuscular blockade.

You may not be able to join if

  • I am under the age of 18.
  • I am over the age of 80.
  • I have end stage renal disease.
  • I require dialysis.
  • I am pregnant.
  • I am in the correctional system.
  • I have a documented allergy to Rocuronium, Sugammadex, Cisatracurium or Neostigmine.
  • My surgery is urgent or requires intubation after the procedure.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is "The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * The subject is able and willing to provide and sign informed consent * The subject must be between 18 and 80 years of age * The subject should have chronic kidney disease as defined by glomerular filtration rate * The surgery must require general anesthesia with endotracheal i…
Contacts

Michael Kinsky, MD

409-772-1011

mkinsky@utmb.edu

CONTACT