Detecting Parkinson's Disease with Colon Tissue Samples

Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

Recruiting Observational Study
PARKINSON DISEASE (Disorder) Parkinson Parkinson's Disease and Parkinsonism Parkinson Disease
No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
40 – 99
Sex
Any
Study type
Observational
Participants needed
20 (estimated)
Sponsor
CND Life Sciences · Other
Who this trial is looking for

This trial is looking for adults with Parkinson's disease to see if proteins in colon samples can help diagnose the condition earlier. Participants will have a colonoscopy as part of their regular check-up for colon cancer or other gut problems.

Are You a Good Fit for This Trial?
Must not be taking Anticoagulants
Rules you out Colon cancerRecent gastrointestinal illnessSignificant cognitive impairment

You may be able to join if

  • I am between 40 and 99 years old
  • I have been diagnosed with Parkinson's disease
  • I have agreed to have a routine colonoscopy

You may not be able to join if

  • I take anticoagulants medication other than allowed ones
  • I have a history of colon cancer
  • I have had a recent gastrointestinal illness or surgery
  • I am pregnant or planning to become pregnant
  • I have significant cognitive impairment
  • I cannot understand that the study is voluntary and for research

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease. The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease? Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and mo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adults 40 to 99 years of age * Patients with a confirmed clinical diagnosis of Parkinson's disease by UKPDS Brain Bank Criteria * Patients who have agreed to undergo a routine colonoscopy as part of their surveillance for colon cancer or exclusion of other gastrointestinal dis…
Contacts

Magda Armendariz Sullivan

503-501-8478

armendam@ohsu.edu

CONTACT