Restructuring the Alpha-Gamma Code in Aging Vision
Recruiting
Early Phase 1
Interventional Study
Aging
Visual Perception
Noninvasive Brain Stimulation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 240 (estimated)
- Sponsor
- Boston University Charles River Campus · Other
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About This Trial
Tests whether age-related visual deficits arise from disrupted alpha-gamma coupling in visual cortex (V1) and MT. Uses fMRI, source-resolved HD-EEG, and personalized complex-waveform HD-tACS to (1) quantify aging effects on phase-amplitude coupling, (2) drive PAC into a preferred "gamma-at-alpha-troughs" state, and (3) bidirectionally change perception by aligning gamma to alpha troughs vs peaks. …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 18+ years of age or older
* normal or corrected-to-normal visual acuity, color vision, and stereo vision
Exclusion Criteria:
* not pregnant,
* no metal implants in head,
* no implanted electronic devices,
* no history of neurological problems or head injury,
* no skin sensit…
Contacts