No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
21,000 (estimated)
Sponsor
Montreal Heart Institute · Other
Who this trial is looking for
This trial is looking for patients who have undergone specific heart valve procedures. Participants will help improve prediction methods and patient outcomes using data from past cases.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least the legal age in my country.
I have had a TAVI with a third generation heart valve and a quality CT scan.
I have had a TMVI with a dedicated device and a quality CT scan.
I have had a TTVI with a dedicated device and a quality CT scan.
I have had a M-TEER with a G4 or newer MitraClip and quality TEE videos.
I have had a T-TEER with a G4 or newer TriClip and quality TEE videos.
You may not be able to join if
I have had a valve-in-valve procedure.
I have had a valve-in-ring procedure.
I have a G3 or older MitraClip.
I have a G1 Pascal device.
I have a G3 TriClip.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This non-interventional study aims to use artificial intelligence to improve the prediction of transcatheter heart valve interventions and optimize patient outcomes. It is based on the analysis of retrospective data from various specialized centers worldwide.
Trial Locations
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Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
Patients who have reached the age of legal majority under local laws.
* For TAVI group: All patients who have had TAVI with a third generation transcatheter heart valve (THV), with an available pre-procedural optimal quality CT scan as defined by an ECG- gating CT with:
1. f…
Inclusion Criteria:
Patients who have reached the age of legal majority under local laws.
* For TAVI group: All patients who have had TAVI with a third generation transcatheter heart valve (THV), with an available pre-procedural optimal quality CT scan as defined by an ECG- gating CT with:
1. five to ten image volumes at cardiac phases from 5% to 95% R-R
2. 0.625 mm slice thickness
3. 0.625 mm spacing between slices
4. 0.88 mm in-plane pixel spacing
* For TMVI group: Patients who have had a TMVI with a dedicated device and screen failures, with an available optimal quality CT scan.
* For TTVI group: Patients who have had a TTVI with a dedicated device and screen failures, with an available optimal quality CT scan.
* For M-TEER: All patient who have had a M-TEER with 1) G4 or newer iteration of MitraClip or 2) G2 or newer iteration of Pascal, with available pre-procedural TEE videos images from one of two vendors: Phillips or GE, with clear identifiable views of the Mitral valve, frame per second equal or higher than 40 frames per second, acceptable 3D reconstructions.
* For T-TEER: All patient who have had a T-TEER with G4 or newer iteration of TriClip or 2) G2 or newer iteration of Pascal, with available pre-procedural TEE videos images from one of two vendors: Phillips or GE, with clear identifiable views of the Tricuspid valve, frame per second equal or higher than 40 frames per second, acceptable transgastric image with acceptable 3D reconstructions.
Exclusion Criteria:
* For TAVI group: Valve-in-valve procedures
* For TMVI group: Valve-in-valve and valve-in-ring procedures
* For TTVI: Valve-in-valve and valve-in-ring procedures
* For M-TEER: G3 or older MitraClip, G1 Pascal
* For T-TEER: G3 Triclip, G1 Pascal
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