FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
Recruiting
Phase 1
Interventional Study
Non-Small Cell Lung Cancer
Colorectal Cancer
Breast Cancer
Ovarian Cancer
Endometrial Carcinoma
Head and Neck Squamous Cell Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 113 (estimated)
- Sponsor
- Fate Therapeutics · Industry
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About This Trial
This is a phase 1 study of FT836 administered in participants with advanced solid tumors. The primary objectives of the study are to evaluate the safety and tolerability of FT836 with or without paclitaxel and/or trastuzumab or cetuximab, and to determine the recommended phase 2 dose (RP2D) of FT836 in combination with trastuzumab or cetuximab; each objective will be assessed with or without pacli…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* For all regimens, disease that is not amenable to curative therapy and that has relapsed or progressed following at least one line of prior systemic therapy.
* Evidence of adequate organ function as determined by all of the following:
* Absolute neutrophil count (ANC) \>100…
Contacts