FT836 for Advanced Solid Tumors

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Recruiting Phase 1 Interventional Study
Non-Small Cell Lung Cancer Colorectal Cancer Breast Cancer Ovarian Cancer Endometrial Carcinoma Head and Neck Squamous Cell Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
119 (estimated)
Sponsor
Fate Therapeutics · Industry
Who this trial is looking for

This trial is looking for people with advanced solid tumors who have not responded to previous treatments. Participants will receive FT836 alone or with other treatments and will be closely monitored for safety and side effects.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have advanced cancer that cannot be cured and has progressed after at least one previous treatment.
  • I have good organ function as shown by my lab results.
  • I have an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1.
  • I have measurable cancer that can be evaluated.
  • I am willing to have biopsies during the study.
  • I have been assessed for disease within 28 days before starting.
  • I have enough healthy organs to qualify for the study.

You may not be able to join if

  • I have significant heart problems or recent heart attack.
  • I have received other cancer treatments within 2 weeks before starting.
  • I have active cancer in my brain.
  • I have had certain brain conditions or medications in the past 6 months.
  • I need immunosuppressive therapy.
  • I have a history of severe side effects from cancer immunotherapy.
  • I have significant nerve damage that affects my daily activities.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial

This is a Phase 1 study of FT836 administered in participants with advanced solid tumors. The primary objectives of the study are to evaluate the safety and tolerability of FT836 with or without chemotherapy and/or trastuzumab or cetuximab, and to determine the recommended phase 2 dose (RP2D) of FT836 with or without chemotherapy and/or trastuzumab or cetuximab

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * For all regimens, disease that is not amenable to curative therapy and that has relapsed or progressed following at least one line of prior systemic therapy. * Evidence of adequate organ function as determined by all of the following: * Absolute neutrophil count (ANC) \>100…
Contacts

Fate Trial Disclosure

858-875-1800

FateTrialDisclosure@fatetherapeutics.com

CONTACT