No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
50 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
165 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for
This trial is looking for people aged 50 and older with hand or wrist osteoarthritis. Participants will compare two treatment options: low-dose radiotherapy and corticosteroid injections.
Are You a Good Fit for This Trial?
Must not be takingOpioid pain medicationOral steroids
Rules you outRheumatoid arthritisPsoriatic arthritisStenosing tenosynovitisDupuytren's contractureFibromyalgiaActive infection
You may be able to join if
I am 50 years old or older
I have hand osteoarthritis
My hand osteoarthritis pain score is 40 or higher on a 100-point scale
I am able to complete study questionnaires
You may not be able to join if
I have had previous surgery on my affected hand
I have an autoimmune joint disease like rheumatoid arthritis
I have a recent injury to my affected hand
I have had a flare of gout or pseudogout in my affected hand
I am currently taking opioid pain medication or oral steroids
I have fibromyalgia or central sensitization syndrome
I am pregnant
I have poorly controlled diabetes
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Patient at Mayo Clinic, Rochester, MN
* Age 50 years or older
* Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
* Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 10…
Inclusion Criteria:
* Patient at Mayo Clinic, Rochester, MN
* Age 50 years or older
* Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
* Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
* Ability to complete study questionnaires
Exclusion Criteria:
* History of previous surgery to the affected hand(s)
* Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
* Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
* Recent injury (within last 1 month) to the affected hand causing current pain
* History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
* Active use of opioid pain medication(s) or oral steroids within the last 3 months
* Fibromyalgia or central sensitization syndrome
* Hand CSI or other hand injection within the past 3 months
* History of hand LDRT within the past 3 months
* Poorly controlled diabetes (HbA1c \> 10%)
* Active infection
* Current pregnancy
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.
