Single Shot Exparel vs Catheters in Lower Extremity Trauma
Recruiting
Phase 4
Interventional Study
Fracture Dislocation of Ankle Joint
Fracture Leg
Fracture Femur
Fracture Lower Leg
Fracture
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Supportive Care
- Participants needed
- 90 (estimated)
- Sponsor
- George Washington University · Other
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About This Trial
This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine. The comparison will be done in patients who receive preoperative adductor and sciatic nerve blocks prior to orthopedic surgery for traumatic lower extremity injury. The patients' pain will then be monitor…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Closed lower extremity orthopedic injury
* Opioid naive patients
* No other significant surgical injuries on admission as determined by study physician
Exclusion Criteria:
* Allergy to local anesthetics
* Multiple traumatic injuries
* Weight less than 60 kg
* Prior opioid us…
Contacts