Kidney Transplant for Heart Health in Chronic Kidney Disease
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
Recruiting
Observational Study
Chronic Kidney Disease
Kidney Transplant
Coronary Microvascular Dysfunction (CMD)
Inflammation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 80 (estimated)
- Sponsor
- Brigham and Women's Hospital · Other
Who this trial is looking for
This trial is looking for people who are candidates for a kidney transplant. Participants will have their heart health measured before and after the transplant to see how it affects their condition.
Are You a Good Fit for This Trial?
You may be able to join if
- I am on the waitlist for a kidney transplant
- I am 45 years or older
- I am between 18 and 44 years old and have been on dialysis for 5 years or more
You may not be able to join if
- I have a left ventricular ejection fraction less than 40%
- I have had coronary artery bypass surgery
- I have had a heart transplant
- I am undergoing revascularization due to pre-transplant cardiac PET
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
People with chronic kidney disease (CKD) often experience faster aging of the heart and blood vessels, which raises the risk of heart problems beyond traditional factors like high blood pressure or cholesterol. One early sign is reduced blood flow in the tiny vessels that supply the heart, measured by a positron emission tomography (PET) scan using a marker called myocardial flow reserve (MFR). In…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Renal transplant candidate on the waitlist
* Age greater or equal to 45 years, or if 18-44 years of age on dialysis for 5 years or more
Exclusion Criteria:
* Left ventricular ejection fraction (LVEF) \< 40%
* History of coronary artery bypass grafting (CABG)
* History of hea…
Contacts