Cemiplimab or Cemiplimab and Fianlimab After Stereotactic Body Radiotherapy in Clear Cell Renal Cell Carcinoma

Recruiting Phase 2 Interventional Study
Clear Cell Renal Cell Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
72 (estimated)
Sponsor
University of Oklahoma · Other
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About This Trial

The purpose of this research is to test the safety of PD-1 inhibitor cemiplimab with or without LAG-3 inhibitor fianlimab, and see what effects (good and bad) of cemiplimab either alone or combined with fianlimab has on patients with oligometastatic clear cell renal cell carcinoma after completion of radiation therapy.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patient must be \>= 18 years of age. * Patient must have a biopsy/pathologically (histologically or cytologically) proven diagnosis of clear cell renal cell carcinoma (ccRCC) prior to randomization. * Patient must have at least 1 and not more than 5 metastatic lesions measurab…
Contacts

Ingrid Block

405-271-8777

SCC-IIT-Office@ouhsc.edu

CONTACT

Lead Nurse

405-271-8777

SCC-IIT-Office@ouhsc.edu

CONTACT