Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA
Recruiting
Observational Study
Colorectal Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 600 (estimated)
- Sponsor
- City of Hope Medical Center · Other
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About This Trial
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults (≥18 years old)
* Histologically confirmed colorectal cancer (Stage I-III)
* Availability of pre-treatment plasma samples
* Written informed consent provided
Exclusion Criteria:
* History of other active malignancies within the past 5 years
* Poor sample quality or he…
Contacts