Cangrelor Infusion for Coronary Arterial Disease

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

Recruiting Phase 4 Interventional Study
Coronary Arterial Disease (CAD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
50 (estimated)
Sponsor
University of Florida · Other
Who this trial is looking for

This trial is looking for patients with coronary arterial disease who are currently receiving a specific dose of cangrelor treatment. Taking part involves being monitored for how well your platelets are reacting to the medication.

Are You a Good Fit for This Trial?
Must not be taking P2Y12 inhibitorsoral anticoagulantsglycoprotein IIb/IIIa inhibitors

You may be able to join if

  • I am at least 18 years old
  • I have been receiving cangrelor treatment for at least two hours
  • I can provide written consent to participate

You may not be able to join if

  • I need urgent surgery
  • I am pregnant or breastfeeding
  • I have taken certain blood thinners in the last 48 hours
  • I am allergic to cangrelor or related medications

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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Check Your Eligibility
About This Trial

The primary aim of this study is to determine rates of patients with optimal platelet reactivity range, defined as PRU levels between 85 and 208, when using a (PFT)-guided titration of cangrelor infusion rate (cangrelor titration) compared to 0.75 mcg/kg/min (standard-dose infusion) for bridging.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Any patient receiving bridging with standard-dose cangrelor infusion rate of 0.75 mcg/Kg/min for at least two hours as part of their standard of care. 2. Age ≥18 years 3. Provide written informed consent. Exclusion Criteria: 1. Need for urgent surgery 2. Confirmed or suspec…
Contacts

Luis Ortega-Paz, MD, PhD

904-244 2060

Luis.Ortega@jax.ufl.edu

CONTACT

Andrea Burton, MPH, CCRP

904-244-5617

Andrea.Burton@jax.ufl.edu

CONTACT