Opioid Use and Breathing After Surgery
Timing of Opioid Administration and Postoperative Respiratory Depression.
Recruiting
Observational Study
Respiratory Complications
Opioid Induced Respiratory Depression
Postoperative Respiratory Complications
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 85
- Sex
- Any
- Study type
- Observational
- Participants needed
- 52 (estimated)
- Sponsor
- Wayne State University · Other
Who this trial is looking for
This trial is looking for adults aged 18 to 85 who will receive general anesthesia and opioids after surgery. Participants will help researchers understand how timing of opioid administration affects breathing after the procedure.
Are You a Good Fit for This Trial?
You may be able to join if
- I have given written informed consent
- I am at least 18 years old
- I am 85 years old or younger
- I am planned for general anesthesia for at least 2 hours
- I expect to receive opioids after my surgery
You may not be able to join if
- I am having a non-operative procedure like imaging
- I will not be admitted to the recovery room after surgery
- I will use a patient-controlled analgesia system
- I am pregnant or breastfeeding
- I have breathing problems in one of my lungs
- I have been classified as ASA V by my doctor
- I am having emergency surgery
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
The goal of this study is to determine if a relationship can be detected between the administration of an opioid and quantitative respiratory depression in spontaneously breathing non-intubated patients who have undergone general anesthesia and have received perioperative opioids.
The primary aim is to determine the temporal effect of opioid administration on respiratory depression as assessed by…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Written informed consent
* Adults ≥18 years of age and ≤85 years of age
* Patients planned for general anesthesia with an expected anesthetic time of at least 2 hours
* Patients expected to receive postoperative opioid analgesia
Exclusion Criteria:
* Non-operative procedure …
Contacts