Gocatamig and Infinatamab for Extensive Stage Lung Cancer

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

Recruiting Phase 1 Phase 2 Interventional Study
Small Cell Lung Cancer Extensive Stage
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
170 (estimated)
Sponsor
Merck Sharp & Dohme LLC · Industry
Who this trial is looking for

This trial is looking for people with extensive-stage small cell lung cancer. Participants will receive two study medicines, Gocatamig and Infinatamab, in hopes of finding a new way to treat this condition.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with extensive-stage small cell lung cancer.
  • I can provide a tumor tissue sample or biopsy.
  • I have completed 3 to 4 cycles of standard chemotherapy recently.
  • I do not have disease progression after my last treatment.
  • I have measurable disease based on imaging results.
  • More than 6 months have passed since my last limited-stage lung cancer treatment.

You may not be able to join if

  • I have a severe lung condition that affects my breathing.
  • I have had any significant heart issues in the past 6 months.
  • I have active autoimmune disease that needs treatment.
  • I have a known active brain tumor.
  • I have received radiation therapy in the last 2 weeks.
  • I have a history of certain serious bleeding issues.
  • I currently have chronic liver disease.
  • I have had a solid organ transplant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial
Researchers are looking for new ways to treat extensive-stage small cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread throughout the lung, to the other lung, or to other parts of the body. A standard (usual) treatment for ES-SCLC uses both chemotherapy and immunotherapy. * Chemotherapy is a treatment that works to destroy cancer cells or stop them from growing. * Immun…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Has a histologically or cytologically confirmed diagnosis of extensive-stage small cell lung cancer (ES-SCLC) * For participants receiving gocatamig + ifinatamab deruxtecan (I-DXd) in maintenance only: …
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