Dietary Nitrate Study for High Blood Pressure in Kids
Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension
Recruiting
Observational Study
Primary Hypertension
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 10 – 18
- Sex
- Any
- Study type
- Observational
- Participants needed
- 48 (estimated)
- Sponsor
- Yelda Kasımoğlu · Other
Who this trial is looking for
This trial is looking for children and teenagers aged 10 to 18 with high blood pressure. Participants will have their oral health checked, provide a saliva sample, and answer questions about their diet and health.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between the ages of 10 and 18.
- I have been diagnosed with primary hypertension.
- I do not have any chronic diseases other than hypertension.
- I have not used mouthwash in the last 3 months.
- I have no allergies to nitrate-rich foods.
You may not be able to join if
- I am younger than 10 years or older than 18 years.
- I have secondary hypertension or heart failure.
- I have a systemic disease.
- I have periodontal disease or a dental infection.
- I have received antibiotic treatment in the last 3 months.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Children and adolescents with primary hypertension (high blood pressure without an underlying secondary cause) are at increased risk of cardiovascular disease in adulthood. Recent research suggests that not only the heart and blood vessels, but also the bacteria living in the mouth may play a role in blood pressure regulation. Certain oral bacteria can convert nitrate from food into nitrite and th…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Applied to the Istanbul University Faculty of Medicine, Department of Pediatric Nephrology,
* Between the ages of 10 and 18,
* Diagnosed with primary hypertension,
* Clinically excluded from secondary hypertension or heart failure,
* No systemic or chronic disease other than h…
Contacts