A Comparative Study of Eleveld and Schnider Pharmacokinetic Models for Target-Controlled Infusion of Propofol in Sedation of Mechanically Ventilated ICU Patients
Recruiting
Observational Study
Intensive Care Unit Sedation
Sedation
Target Controlled Infusion of Propofol
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 84 (estimated)
- Sponsor
- Hacettepe University · Other
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About This Trial
This prospective observational study aims to compare the clinical performance of two target-controlled infusion (TCI) models, Eleveld and Schnider, for propofol sedation in mechanically ventilated intensive care unit (ICU) patients. The study evaluates sedation depth, hemodynamic stability, and recovery profiles using the Bispectral Index (BIS) and Riker Sedation-Agitation Scale. Secondary outcome…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Age over 18 years,
Classified as ASA (American Society of Anesthesiologists physical status) class I-IV,
Being monitored in the Anesthesiology and Reanimation Intensive Care Unit of Hacettepe University Faculty of Medicine Hospital,
Availability of necessary data (medical his…
Contacts