Role of the Noradrenergic System in the Regulation of Learning Dynamics: Evaluation of the Effect of a Low-dose Selective Noradrenaline Reuptake Inhibitor (NOISYXETINE)
Recruiting
N/A
Interventional Study
Role of the Noradrenergic System in the Regulation of Learning Dynamics
No Disease or Condition is Being Studied
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 39
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 160 (estimated)
- Sponsor
- Centre Hospitalier St Anne · Other
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About This Trial
Administration of low-dose selective noradrenaline reuptake inhibitor (sNRI) (e.g. atomoxetine) to healthy subjects is a validated model of increasing cortical noradrenaline levels which, combined with computational modelling of behaviour, allows fine-grained analysis of the impact on learning processes of noradrenaline's fluctuations in the human cortex.
The study goal is to characterize the mod…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Right-handed, assessed by the Edinburgh scale;
* Written signed informed consent;
* Subject covered by a social security regimen.
Exclusion Criteria:
* Pregnant, parturient or breastfeeding woman;
* First-degree family history of axis I disorder (DSM-IV-TR), excepted unipola…
Contacts