The Role and Regulatory Mechanism of Germinal Center Immune Response in Hepatitis B Virus Infection

Recruiting Observational Study
Hepatitis B Virus Infection
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
280 (estimated)
Sponsor
Nanfang Hospital, Southern Medical University · Other
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About This Trial
The purpose of this observational study is to investigate the structure and composition of germinal centers in individuals with chronic HBV infection. The primary questions it aims to address are: What are the phenotypes, functions, and complexity of B cell clones of the immune cells within the germinal centers of chronic HBV-infected individuals? Do chronic HBV-infected individuals have ectopic …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Male or female, patients with chronic hepatitis B and hepatitis B surface antigen negative patients with clinical diagnosis who need to undergo liver, spleen, tonsil or lymph node surgery. 2. Before performing any research-related steps, the patient understood the research pr…
Contacts

Yongyin Li

+8613826039505

yongyinli@foxmail.com

CONTACT