Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients treated at expert centers.
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Eligibility Criteria
Inclusion Criteria:
* Patients older than 18 years
* Patients able to give informed consent
* Histologically confirmed pancreatic adenocarcinoma
* LAPC stage according to NCCN10 at diagnosis (Figure 1)
* Received at least 4 months of induction chemotherapy
* RECIST 1.1 stable disease (SD) or partia…
Inclusion Criteria:
* Patients older than 18 years
* Patients able to give informed consent
* Histologically confirmed pancreatic adenocarcinoma
* LAPC stage according to NCCN10 at diagnosis (Figure 1)
* Received at least 4 months of induction chemotherapy
* RECIST 1.1 stable disease (SD) or partial response (PR) after induction therapy
* Patient considered eligible for radical resection by local MDT
Exclusion Criteria:
* Informed consent withdrawal
* Presence of tumor characteristics precluding surgery
* Presence of patient significant comorbidities precluding surgery
* Unavailable pre-induction therapy abdominal imaging
* Pathological confirmation of any tumor different from PDAC
Contacts
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