Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries

Inclusion Criteria: * Aged 12 years or older * Mature maxillary or mandibular permanent tooth with extremely deep restorations/caries penetrating the entire thickness of dentine on the radiograph without a radiopaque zone separating the lesion from the pulp (Bjorndal et al., 2019) * Tooth may or may not be symptomatic at the time of recruitment but must be responsive to cold and EPT sensibility testing * Tooth is restorable and can be adequately isolated during treatment * One tooth per patient Exclusion Criteria: * Teeth with difficult access and unpredictable isolation using a rubber dam * Teeth aberrant root canal morphology, extreme root curvatures (\>30 degrees), calcified canals/sclerosed pulp * Teeth indicated for elective root canal treatment for restorative purposes * Teeth with apical periodontitis * Presence of apical radiolucency * Any evidence of purulence or excessive bleeding that cannot be controlled with a cotton pellet with 1.25% hypochlorite for 10 minutes * History of trauma to the tooth * Teeth with active periodontal disease (pocket depth \>5mm) * Patients with complex medical histories that may affect their caries experience and healing ability (immunocompromised, radiotherapy etc.) * Patients who are pregnant or breast-feeding * Patients who are unable to consent