JN002 for the Treatment of Dry Eye Disease
Recruiting
Early Phase 1
Interventional Study
Dry Eye
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 30 (estimated)
- Sponsor
- Eye & ENT Hospital of Fudan University · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This is a first-in-human, single-center, randomized, double-blind, placebo-controlled clinical trial designed to:·Evaluate the efficacy of JN002 Ophthalmic Solution in treating dry eye disease (DED)·Assess the safety of JN002 Ophthalmic SolutionResearchers will compare three groups-placebo (vehicle), low-dose JN002 (0.05 mg/mL), and high-dose JN002 (0.1 mg/mL)-to evaluate whether JN002 Ophthalmic …
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
1. Aged 18 years or older
2. Ocular Surface Disease Index (OSDI) score ≥ 13
3. Schirmer I test result ≤ 10 mm/5 min
4. Fluorescein tear film break-up time \< 10 seconds
5. Corneal Fluorescein Staining score (National Eye Institute grading) ≥ 4
6. Best corrected visual acuity ≥ 0…
Contacts