Comparing Haloperidol to Olanzapine in the Treatment of Suspected Cannabinoid Hyperemesis in the Emergency Department

Recruiting Phase 3 Interventional Study
Cannabinoid Hyperemesis Syndrome
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 100
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
114 (estimated)
Sponsor
Mercy Bon Secours Saint Vincent Medical Center · Other
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About This Trial

The aim of the study is to identify which medication (haloperidol or olanzapine) is most effective in treating nausea and abdominal pain associated with cannabinoid hyperemesis using a 10-point visual analog scale with intervals of 0.5.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * subjects must meet ONE of the below criteria AND are a near-daily to daily user of cannabis by inhalation for greater than or equal to 6 months. 1. Have documented previous diagnosis of cannabinoid hyperemesis, or 2. Report (or on chart review) greater than or equal to 3 …
Contacts

Joseph Jabour, DO FACEP

3303476487

jabourj1@gmail.com

CONTACT

Amanda Gutek

agutek@mercy.com

CONTACT